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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK7
All Species:
20.61
Human Site:
Y27
Identified Species:
30.22
UniProt:
P50613
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P50613
NP_001790.1
346
39038
Y27
E
G
Q
F
A
T
V
Y
K
A
R
D
K
N
T
Chimpanzee
Pan troglodytes
XP_518193
305
34323
L28
E
I
K
L
L
Q
E
L
S
H
P
N
I
I
G
Rhesus Macaque
Macaca mulatta
XP_001092242
346
39008
Y27
E
G
Q
F
A
T
V
Y
K
A
R
D
K
N
T
Dog
Lupus familis
XP_850424
354
39795
Q35
S
P
D
C
P
G
L
Q
R
P
E
T
K
N
T
Cat
Felis silvestris
Mouse
Mus musculus
Q03147
346
38950
Y27
E
G
Q
F
A
T
V
Y
K
A
R
D
K
N
T
Rat
Rattus norvegicus
P51952
329
37122
A31
K
N
T
N
Q
I
V
A
I
K
K
I
K
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506541
324
36280
A29
K
L
G
H
R
S
E
A
K
D
G
I
N
R
T
Chicken
Gallus gallus
P13863
303
34670
G27
K
G
R
H
K
T
T
G
Q
V
V
A
M
K
K
Frog
Xenopus laevis
P20911
352
39672
Y33
E
G
Q
F
A
T
V
Y
K
A
R
D
K
N
T
Zebra Danio
Brachydanio rerio
A8WIP6
344
39006
A36
T
V
A
L
K
K
V
A
L
R
R
L
E
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511044
353
39655
Y27
E
G
Q
F
A
T
V
Y
K
A
R
D
T
V
T
Honey Bee
Apis mellifera
XP_395800
321
36188
R31
K
D
S
R
A
E
A
R
D
G
I
N
R
T
A
Nematode Worm
Caenorhab. elegans
P34556
332
38277
Y37
E
G
T
Y
G
V
V
Y
K
G
K
N
R
R
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
A21
T
Y
G
V
V
Y
K
A
L
D
K
A
T
N
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT0
391
44511
F27
Q
G
T
Y
G
V
V
F
K
A
T
D
T
K
T
Baker's Yeast
Sacchar. cerevisiae
P06242
306
35228
H27
V
V
Y
L
G
C
Q
H
S
T
G
R
K
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.1
99.7
92.6
N.A.
95
91
N.A.
87.5
39.8
85.2
42.2
N.A.
65.7
63.8
39.3
N.A.
Protein Similarity:
100
88.1
99.7
95.4
N.A.
96.8
92.4
N.A.
88.7
56.3
90.3
59.5
N.A.
78.4
75.1
57.5
N.A.
P-Site Identity:
100
6.6
100
20
N.A.
100
13.3
N.A.
13.3
13.3
100
13.3
N.A.
86.6
6.6
40
N.A.
P-Site Similarity:
100
20
100
33.3
N.A.
100
26.6
N.A.
26.6
33.3
100
26.6
N.A.
86.6
26.6
66.6
N.A.
Percent
Protein Identity:
N.A.
39.3
N.A.
49.1
41
N.A.
Protein Similarity:
N.A.
57.8
N.A.
65.2
60.6
N.A.
P-Site Identity:
N.A.
6.6
N.A.
40
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
60
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
38
0
7
25
0
38
0
13
0
0
13
% A
% Cys:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
0
0
0
7
13
0
38
0
7
0
% D
% Glu:
44
0
0
0
0
7
13
0
0
0
7
0
7
0
7
% E
% Phe:
0
0
0
32
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
50
13
0
19
7
0
7
0
13
13
0
0
0
19
% G
% His:
0
0
0
13
0
0
0
7
0
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
7
0
0
7
0
7
13
7
13
0
% I
% Lys:
25
0
7
0
13
7
7
0
50
7
19
0
44
13
7
% K
% Leu:
0
7
0
19
7
0
7
7
13
0
0
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
7
0
7
0
0
0
0
0
0
0
19
7
38
0
% N
% Pro:
0
7
0
0
7
0
0
0
0
7
7
0
0
0
0
% P
% Gln:
7
0
32
0
7
7
7
7
7
0
0
0
0
0
0
% Q
% Arg:
0
0
7
7
7
0
0
7
7
7
38
7
13
13
0
% R
% Ser:
7
0
7
0
0
7
0
0
13
0
0
0
0
0
0
% S
% Thr:
13
0
19
0
0
38
7
0
0
7
7
7
19
7
57
% T
% Val:
7
13
0
7
7
13
57
0
0
7
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
13
0
7
0
38
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _